Tools for Predictive Microbial Modelling and QMRA

A list of tools for predictive modeling in food and quantitative microbial risk assessment

Tool/ResourceDescriptionTopic
@RiskExcel add-in that uses Monte Carlo simulation to analyze risk and uncertainty in decision-making, showing the probability of various outcomes and supporting risk analysis.Quantitative Microbial Risk Assessment (QMRA)
A swift Quantitative Microbiological Risk Assessment tool (sQMRA)Simplified Excel-based Quantitative Microbiological Risk Assessment tool for comparing pathogen-food risks from retail to illness, including cross-contamination and food preparation stages.Quantitative Microbial Risk Assessment (QMRA)
biogrowth (R package)R package for modeling microbial growth under static and dynamic conditions in predictive microbiology, offering model fitting and growth predictions.Predictive Microbial Modeling (PMM)
Fitting Tool
biogrowth-web (Shiny app)Web app for microbial growth modeling using an interactive interface, allowing users to predict microbial growth and fit models under static and dynamic conditions.Predictive Microbial Modeling (PMM)
Fitting Tool
Bioinactivation (R package)R package for microbial inactivation modeling, supporting predictions and model fitting under isothermal and non-isothermal conditions for use in predictive microbiology.Predictive Microbial Modeling (PMM)
Fitting Tool
Bioinactivation (Shiny app)Web app for microbial inactivation, providing interactive tools for fitting inactivation models and making predictions under static and dynamic conditions.Predictive Microbial Modeling (PMM)
Fitting Tool
Bioinactivation FEWeb interface for microbial inactivation modeling, offering easy model fitting and prediction generation under both isothermal and non-isothermal conditions.Predictive Microbial Modeling (PMM)
Fitting Tool
Prediction Tool
Cardinal Fit (Shiny app)Shiny app for fitting cardinal parameter models in predictive microbiology, estimating microbial growth conditions like temperature and pH from challenge study data.Predictive Microbial Modeling (PMM)
Fitting Tool
ComBaseOnline resource for quantitative and predictive food microbiology, featuring a database of microbial growth and survival data, aiding in risk management and food safety modeling.Predictive Microbial Modeling (PMM)
Model Repository
Quantitive Microbial Risk Assessment (QMRA)
Control Measures Validation (FSO) ToolSpreadsheet tool to explore the ICMSF Food Safety Objective (FSO) equation for determining product compliance in processes affected by variability, useful for validating food safety control measures.Other Resources
D-database microbial inactivation data in foodsDatabase compiling over 2,000 microbial inactivation models from peer-reviewed studies, emphasizing variability in microbial responses and providing tools like meta-regression with mixed-effects models.Other Resources
DMFitApplication for fitting bacterial growth curves, allowing users to visualize microbiological growth/survival data and apply models, with nonlinear least squares and regression coefficient calculations.Predictive Microbial Modeling (PMM)
Fitting Tool
DMRI – predictive models for meatPredictive models for meat safety and shelf life, simulating bacterial growth based on user input. Offers consultancy services and predictive modeling courses on topics like Listeria and pathogen inactivation.Predictive Microbial Modeling (PMM)
Prediction Tool
E. coli Inactivation in Fermented Meats ModelExcel-based tool for calculating E. coli inactivation in fermented meat products by inputting fermentation and maturation conditions, supporting isothermal and dynamic scenarios with easy data entry.Predictive Microbial Modeling (PMM)
Prediction Tool
EFSA Comprehensive European Food Consumption DatabaseDatabase offering detailed food consumption data across the EU, essential for food hazard risk evaluation and exposure estimation, helping tailor risk assessments based on dietary surveys by age and food group.Other Resources
EFSA Knowlege Junction (KJ)Open repository for sharing food and feed safety risk assessment evidence and materials, promoting transparency and reuse, with submissions receiving DOIs and metadata for tracking.Other Resources
EFSA zoonoses, antimicrobial resistance and food-borne outbreaksDirective-mandated data collection on zoonoses, antimicrobial resistance, and foodborne outbreaks across the EU, analyzed and published by EFSA in annual reports in collaboration with ECDC.Other Resources
Emerging Zoonoses Information and Priority systems (EZIPs)Resource for prioritizing emerging zoonoses based on threat criteria, featuring a ranked database of zoonotic pathogens and an interactive tool for exploring and adding new pathogens.Other Resources
FDA’s Fresh Produce Risk Ranking ToolSemi-quantitative tool identifying high-risk pathogen-produce combinations in the U.S. food supply, based on outbreak data, customizable in Microsoft Access with guidance and peer review support.Other Resources
FDA-iRISKWeb-based risk-assessment tool for comparing and ranking microbial and chemical hazards in food, simulating food safety scenarios across the supply chain, with advanced features like Monte Carlo simulations and predictive microbial models.Quantitative Microbial Risk Assessment (QMRA)
FISHMAPSoftware that predicts spoilage bacteria growth in fish products under modified atmosphere packaging (MAP), comparing experimental data with models, and saving results in Excel format for easy analysis.Predictive Microbial Modeling (PMM)
Prediction Tool
fitdistrplus (R package)Statistical package for fitting univariate parametric distributions to censored/non-censored data, offering functions for estimation, goodness-of-fit assessment, and uncertainty quantification, useful in risk assessment and data analysis.Quantitative Microbial Risk Assessment (QMRA)
Food and Ecological Systems Modelling Journal (FESMJ)Open-access journal publishing models, datasets, and software solutions in agriculture, food systems, bioeconomy, and environmental sciences, emphasizing research outcomes like model validation and data analytics pipelines.Other Resources
Food Commodity Intake Database (FCID)U.S. EPA database translating food consumption into defined commodities, enhancing dietary exposure assessments for pesticides, supporting risk assessment models for the U.S. population.Other Resources
Food Spoilage and Safety Predictor (FSSP)Free software for predicting microbial growth and shelf-life under various conditions, including spoilage and pathogens in food, with customizable inputs like temperature, pH, and salt content.Predictive Microbial Modeling (PMM)
Prediction Tool
FoodProcess-LabOpen-source extension for microbial modeling integrated into food and feed industry processes, tracking microbial growth and inactivation to support risk assessment and industry monitoring.Other Resources
foodrisk.org TutorialsTutorials on risk analysis in food safety, featuring FDA-iRISK webinars and risk communication/assessment tutorials, offering practical guidance and accessible resources for food safety professionals.Tutorial
FOSCOLLAB: a global platform for food safety data and information Collaborative platform offering access to risk assessment reports, food consumption data, and raw contamination data from global sources like JECFA and FAO/WHO, aiding risk analysis and decision-making.Other Resources
FRISBEEEuropean initiative enhancing refrigeration technologies in the food cold chain, integrating food quality, safety, energy efficiency, and environmental impacts, supported by the open-access ColdBase database.Other Resources
FSK-LabOpen-source KNIME extension for working with FSKX food safety models, supporting model creation, editing, import/export, and running models in R or Python. Developers can contribute via GitHub.Quantitative Microbial Risk Assessment (QMRA)
GInaFiTFree Excel add-in for testing nine microbial survival models, offering automatic statistical reports and model comparisons based on experimental data, with built-in safeguards for accurate use.Predictive Microbial Modeling (PMM)
Fitting Tool
GroPINPredictive modeling database featuring microbial growth and inactivation models for pathogens and spoilage organisms, with models considering intrinsic and extrinsic factors, regularly updated for scientific and industrial use.Predictive Microbial Modeling (PMM)
Prediction Tool
Model Repository
growth rates (R package)R package for estimating microbial growth rates from batch or plate reader data, using multiple methods for model fitting, including linear regression, nonlinear models, and smoothing splines.Predictive Microbial Modeling (PMM)
Fitting Tool
Heavy Metal Screening ToolRisk assessment tool for evaluating public health risks from heavy metals in food, providing hazard characterization, dietary exposure assessment, and risk characterization using publicly available data.Other Resources
Interactive online Catalogue on Risk Assessment (ICRA)Downloadable tool for comparing microbial risk assessment models, offering a wide range of pathogen and commodity comparisons for microbial risk analysis.Quantitative Microbial Risk Assessment (QMRA)
Model Repository
IPMPUser-friendly software for analyzing microbial growth and inactivation data, supporting a range of models for predictive microbiology, and evaluating temperature effects on growth rates.Predictive Microbial Modeling (PMM)
Fitting Tool
Lis-RA (Excel spreadsheet)Risk assessment model for estimating listeriosis cases in the EU based on RTE foods, featuring Excel-based inputs and outputs, requiring @Risk software for optimal performance.Quantitative Microbial Risk Assessment (QMRA)
Listeria Cardinal ModelCardinal parameter model for Listeria monocytogenes growth, estimating temperature, pH, and water activity thresholds for growth, developed using broth data from growth experiments.Predictive Microbial Modeling (PMM)
Prediction Tool
Listeria monocytogenes generic Quantitative Microbiological Risk Assessment (gQMRA) modelExcel-based model assessing Listeria contamination in ready-to-eat foods, supporting uncertainty evaluation and dose-response variability, developed using flexible inputs for different food categories.Quantitative Microbial Risk Assessment (QMRA)
mc2d (R package)R package for two-dimensional Monte Carlo simulations (Second-Order Monte Carlo), supporting various distributions such as pert, triangular, and empirical. Requires R version 2.10.0 or higher, with dependencies on libraries like stats and ggplot2.Quantitative Microbial Risk Assessment (QMRA)
Microbial Responses Viewer (MRV)Database focused on microbial growth/no-growth data for 19 microorganisms. Provides access to growth rates influenced by temperature, pH, and water activity, modeled with generalized linear models.Predictive Microbial Modeling (PMM)
Prediction Tool
Model Repository
Microbiological Sampling Plan Analysis Tool (JEMRA)Tool for designing and evaluating microbiological sampling plans, assessing risk reduction and detection effectiveness for contaminated product lots.Other Resources
Microbiological Sampling Plans Tool (ICMSF Spreadsheet)Spreadsheet tool for exploring ICMSF microbial safety recommendations, calculating acceptance probabilities using a lognormal distribution, with support for three-class sampling plans.Other Resources
MicroHibroRisk assessment tool integrating microbial kinetics and dose-response models to predict microorganism growth or inactivation in food, supporting food safety and hygiene evaluations.Predictive Microbial Modeling (PMM)
Prediction Tool
Model Repository
Quantitative Microbial Risk Assessment (QMRA)
Microrisk Lab (Shiny app)Online freeware for microbial kinetic analysis, offering modules for fitting isothermal and non-isothermal models, as well as deterministic and stochastic simulations.Predictive Microbial Modeling (PMM)
Fitting Tool
MLA Refrigeration Index CalculatorPredictive model for E. coli growth on meat, based on temperature, pH, water activity, and lactate concentration. Allows users to enter product temperature data to estimate E. coli growth.Predictive Microbial Modeling (PMM)
Prediction Tool
ModelAssistFree risk analysis training tool offering practical examples, a searchable database, and instructional videos to support consistent risk analysis practices.Other Resources
nlsMicrobio (R package)R package for nonlinear regression in predictive microbiology, providing models and data sets for microbial growth analysis. Built on the stats and nlstools packages, tailored for microbiology research.Predictive Microbial Modeling (PMM)
Fitting Tool
openFSMRCommunity-driven search engine for predictive microbial models, offering models for various microorganisms, including growth and inactivation data gathered from multiple repositories.Predictive Microbial Modeling (PMM)
Model Repository
Prediction Tool
OptiPaMATLAB-based GUI for simulating and calibrating ordinary differential equation (ODE) models, designed for food research. Simplifies parameter estimation, sensitivity analysis, and confidence interval generation, accessible to researchers with minimal programming skills.Predictive Microbial Modeling (PMM)
Fitting Tool
Pathogen Modeling Program (PMP)Predictive models for foodborne bacteria growth and inactivation under various environmental conditions. The tool is continuously updated, and validation is encouraged for accurate use.Predictive Microbial Modeling (PMM)
Prediction Tool
Model Repository
Pathogens in Foods (Database)Web application aggregating and analyzing microbial hazard occurrence data in foods across Europe, with around 6,000 observations. Offers summary statistics, meta-analyses, and regular usability updates.Other Resources
Perfringens PredictorUser-friendly simulation tool for predicting Clostridium perfringens behavior during the cooling of bulk cooked meats. Allows inputs for pH, salt concentration, and product type (cured or uncured).Predictive Microbial Modeling (PMM)
Prediction Tool
PMM-LabOpen-source extension for KNIME, providing tools for microbial data analysis, predictive model development, and storage of experimental data in an HSQL database.Predictive Microbial Modeling (PMM)
Fitting Tool
Prediction Tool
PraedicereFree web-based tool offering predictive microbiology modules for modeling pathogen growth and probability under varying conditions, with results exportable in CSV, Excel, or PDF.Predictive Microbial Modeling (PMM)
Prediction Tool
PredOxyPackSoftware simulating oxygen evolution in custom packaging, allowing users to compare packaging designs, materials, and temperatures. Generates graphical results and exports to Excel or PDF.Other Resources
Process lethality determination spreadsheetModel for validating heat treatment effectiveness in food processing, helping users determine microbial destruction throughout heating and cooling cycles to ensure safety.Predictive Microbial Modeling (PMM)
Prediction Tool
QMRA WikiComprehensive resource for Quantitative Microbial Risk Assessment (QMRA), offering data and tools for hazard identification, dose-response, exposure assessment, and risk management. Open to contributions from the community.Tutorial
RAKIP -Web Model RepositoryPortal for downloading risk assessment models and data in standardized formats, facilitating knowledge exchange and integration with various software tools, part of the RAKIP initiative.Predictive Microbial Modeling (PMM)
Prediction Tool
Model Repository
Quantitative Microbial Risk Assessment (QMRA)
Risk RangerThis tool assists with microbial food safety risk assessments by adjusting hazard severity and serving frequency to improve accuracy. Primarily used for teaching and ranking pathogen-product risks, it relies on the quality of input data.Quantitative Microbial Risk Assessment (QMRA)
Salmonella in eggs (Shiny app)A model that estimates salmonellosis cases per million servings of table eggs and the probability of illness per serving. It describes potential Salmonella Enteritidis contamination from farm to fork, accounting for time/temperature storage and consumption practices.Quantitative Microbial Risk Assessment (QMRA)
Shelf Stability PredictorPredicts the growth of Listeria monocytogenes and Staphylococcus aureus on fully cooked, ready-to-eat (RTE) meat products. It bases its predictions on pH and water activity and applies only to products that are fully cooked and dried for shelf stability.Predictive Microbial Modeling (PMM)
Prediction Tool
Sym’PreviusA decision support software for predicting bacterial growth, growth/no-growth boundaries, and thermal inactivation. This tool includes modules for fitting microbiological data and simulating pathogen and spoilage organism behavior. The free version provides fitting tools for growth curves and inactivation parameters.Predictive Microbial Modeling (PMM)
Prediction Tool
The European Surveillance System (TESSy)A data collection and analysis platform for communicable diseases in EU and EEA countries, launched in 2008. It consolidates previous systems into a single resource for high-quality public health analysis and actionable insights.Other Resources
Therm 2.0Predictive tool for assessing food safety risks in raw meat and poultry, especially during temperature abuse, focusing on Salmonella and Staphylococcus aureus. It evaluates products like pork, sausage, beef, and poultry intended for thorough cooking, including seasoned items.Predictive Microbial Modeling (PMM)
Prediction Tool
Webinar QMRA Better food safety control in the food chainThis one-hour webinar provides a comprehensive overview of risk assessment and explores predictive modeling of microbial growth, with an emphasis on Quantitative Microbial Risk Assessment (QMRA) and its food safety applications.Tutorial